I used stcox to evaluate risk of outcome x associated with ever-never
exposure to y. I am now
interested in a dose-response analysis for all number of doses of y. Sometimes subsequent doses are
received in a matter of weeks, sometimes they are received years after the
first dose. Should I create separate records for each period of follow-up
at a given number of doses? If I do this, is there any reason to maintain
multiple-observation per subject data? Or can the records at each number of
doses be analyzed as separate subjects? I ask this last point because it
is a HUGE dataset (> 10^6).
Thanks, Will
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