Dear list
Using Stata 8.1
I'm unsure on how to calculate the required sample for the following trial,
been searching by findit for equivalence ado's without finding my answer:
We are planning to do a 2 year equivalence trial.The current standard of
treatment has a 2 year failure rate of 7%: In our trial of a new drug, the
treatments will be considered equivalent if the 95% confidence interval are
within the bound of -12% to 12%, which we believe is the the largest
difference that would be considered clinically acceptable.
any suggestions?
Jannik Helweg-Larsen
*
* For searches and help try:
* http://www.stata.com/support/faqs/res/findit.html
* http://www.stata.com/support/statalist/faq
* http://www.ats.ucla.edu/stat/stata/
