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From | prymkiewicz <peter.rymkiewicz@gmail.com> |
To | statalist@hsphsun2.harvard.edu |
Subject | st: Survival Analysis estat phtest with very large sample size--need help |
Date | Thu, 5 Dec 2013 18:26:26 -0800 (PST) |
Hi, I need a bit of help. I am doing a survival analysis on a large population ~435732 people. I have been testing the PH assumption using estat phtest and schoenfled residuals. I believe that the large sample size is causing the phtest indicate evidence against the PH assumption while the schoenfeld plot would indicate that the model variables adheres to the PH assumption. I have included the global and individual variable tests, as well as the plot for one of our variables (mets). Could you let me know the cause of this and could you let me know if there are alternative methods or references in literature acknowledging the phtest and alternative methods for very large study populations. Thanks, Peter . estat phtest, detail Test of proportional-hazards assumption Time: Time ---------------------------------------------------------------- | rho chi2 df Prob>chi2 ------------+--------------------------------------------------- male | 0.01247 11.18 1 0.0008 age | 0.05331 252.06 1 0.0000 0b.urban | . . 1 . 1.urban | -0.01640 19.44 1 0.0000 99.urban | -0.00225 0.36 1 0.5472 1b.quintile | . . 1 . 2.quintile | -0.00620 2.74 1 0.0976 3.quintile | -0.00745 3.98 1 0.0461 4.quintile | -0.00025 0.00 1 0.9457 5.quintile | -0.00311 0.70 1 0.4039 99.quintile | -0.00119 0.10 1 0.7499 mi_1 | -0.00795 4.63 1 0.0314 chf_1 | -0.02492 47.01 1 0.0000 pvd_1 | 0.00206 0.32 1 0.5734 cevd_1 | -0.02076 32.80 1 0.0000 dem_1 | 0.00630 3.05 1 0.0807 copd_1 | -0.01545 17.10 1 0.0000 rheum_1 | -0.00840 5.06 1 0.0245 pub_1 | -0.00712 3.67 1 0.0553 mildld_1 | -0.00959 6.59 1 0.0102 diab_uc_1 | -0.02159 34.32 1 0.0000 diab_c_1 | 0.01731 21.99 1 0.0000 para_1 | -0.01532 17.14 1 0.0000 rd_1 | -0.03307 82.48 1 0.0000 cancer_1 | -0.03237 72.39 1 0.0000 mlsd_1 | -0.00246 0.43 1 0.5099 mets_1 | -0.06236 272.50 1 0.0000 hiv_1 | -0.00863 5.31 1 0.0213 ------------+--------------------------------------------------- global test | 1392.71 26 0.0000 ---------------------------------------------------------------- <http://statalist.1588530.n2.nabble.com/file/n7580460/phtest_plot_mets_1.jpg> -- View this message in context: http://statalist.1588530.n2.nabble.com/Survival-Analysis-estat-phtest-with-very-large-sample-size-need-help-tp7580460.html Sent from the Statalist mailing list archive at Nabble.com. * * For searches and help try: * http://www.stata.com/help.cgi?search * http://www.stata.com/support/faqs/resources/statalist-faq/ * http://www.ats.ucla.edu/stat/stata/