RE: st: How to handle large (or small) odds ratios

[Tim Evans <Tim.Evans@wmciu.nhs.uk>]

David,

Yes I agree; having the very useful 'other'(!!) group would allow me to combined categories with small numbers together - but I guess this can lead to a rather mixed bag.

Thanks once again.

Best wishes

Tim


-----Original Message-----
From: owner-statalist@hsphsun2.harvard.edu [mailto:owner-statalist@hsphsun2.harvard.edu] On Behalf Of David Hoaglin
Sent: 18 May 2012 13:17
To: statalist@hsphsun2.harvard.edu
Subject: Re: st: How to handle large (or small) odds ratios

Hi, Tim.

Thanks for the update.

When a category contains a small number of observations, it is often
necessary to combine it with other categories.

Regards,

David

On Fri, May 18, 2012 at 7:53 AM, Tim Evans <Tim.Evans@wmciu.nhs.uk> wrote:
> Hi David,
>
> Thanks for your response - my table formatting was not quite like that when it was sent!
>
> Having reviewed the data behind the analysis, Ive decided the prudent approach is to remove the staging analysis for those particular adjusted O/Rs as they were based on small numbers. I've also had a look at:
>
> 'How should one interpret 1.00E+00 as the LCI and UCI for Complex mixed
> and stromal?  Is the standard error of that OR so small that the LCI
> and UCI both round to 1.00?  Many other CIs are fairly wide.'
>
> Again, having looked at the number of cases, they are based upon either a single case, or a very small fraction of the total and appear to be behaving in the exact manner as the reference group. Given the apparent lack of robustness here, I've removed these also.
>
> Thanks for helping me to see the obvious. The results I have now are much more sensible.
>
> Best wishes
>
> Tim

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