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st: stratified Cox proportional hazards model and AIC
From
Brigham Whitman <[email protected]>
To
[email protected]
Subject
st: stratified Cox proportional hazards model and AIC
Date
Tue, 1 Nov 2011 00:23:18 -0400
I am using the stcox command to perform a Cox proportional hazards
model, and using the log likelihood in the output, I am computing AICc
values to determine the best model. If anybody has ever done this, I
am trying to find out if I can compare the AICc value for a model that
is stratified (in this case by sex) with the AICc value of a different
model that does not stratify by sex. Can I do this? Or do I need to
compare stratified models together as one suite of models, and
non-stratified models as a different suite of models?
Results from a non-stratified model and a stratified model are below.
Thank you,
Brigham Whitman
stcox velo_log10_ra14 velo_log10_ra14squared sex , nohr
failure _d: event == 3
analysis time _t: (mydate-origin)
origin: time d(01Jan2006)
enter on or after: event==1
exit on or before: event==3 4
id: id
Iteration 0: log likelihood = -37.949901
Iteration 1: log likelihood = -36.376963
Iteration 2: log likelihood = -35.219183
Iteration 3: log likelihood = -33.895999
Iteration 4: log likelihood = -32.808219
Iteration 5: log likelihood = -32.71276
Iteration 6: log likelihood = -32.71274
Refining estimates:
Iteration 0: log likelihood = -32.71274
Cox regression -- Breslow method for ties
No. of subjects = 34 Number of obs = 2406
No. of failures = 14
Time at risk = 2744
LR chi2(3) = 10.47
Log likelihood = -32.71274 Prob > chi2 = 0.0149
------------------------------------------------------------------------------
_t | Coef. Std. Err. z P>|z| [95% Conf. Interval]
-------------+----------------------------------------------------------------
velo_log1~14 | -10.92228 8.79507 -1.24 0.214 -28.1603 6.315739
velo_log10.. | 2.799857 2.81852 0.99 0.321 -2.724341 8.324055
sex | 1.418398 .6191127 2.29 0.022 .2049591 2.631836
------------------------------------------------------------------------------
. stcox velo_log10_ra14 velo_log10_ra14squared , nohr strata(sex)
failure _d: event == 3
analysis time _t: (mydate-origin)
origin: time d(01Jan2006)
enter on or after: event==1
exit on or before: event==3 4
id: id
Iteration 0: log likelihood = -26.357427
Iteration 1: log likelihood = -25.001699
Iteration 2: log likelihood = -24.947868
Iteration 3: log likelihood = -24.947775
Refining estimates:
Iteration 0: log likelihood = -24.947775
Stratified Cox regr. -- no ties
No. of subjects = 34 Number of obs = 2406
No. of failures = 14
Time at risk = 2744
LR chi2(2) = 2.82
Log likelihood = -24.947775 Prob > chi2 = 0.2442
------------------------------------------------------------------------------
_t | Coef. Std. Err. z P>|z| [95% Conf. Interval]
-------------+----------------------------------------------------------------
velo_log1~14 | -6.248969 9.205174 -0.68 0.497 -24.29078 11.79284
velo_log10.. | 1.329912 2.974208 0.45 0.655 -4.499429 7.159252
------------------------------------------------------------------------------
Stratified by sex
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