Re: st: Cox proportional hazard model

[Michael McCulloch <mm@pinestreetfoundation.org>]

Dear Nyasha,
It seems your main outcome is time to employment, and your co-variates  
include:
	# of non-patient household members living together with the patient
	patient receiving AIDS medication (yes/no)

Questions which also occur to me are:
	can you measure duration of AIDS medication prior to start of  
observation in your study?
	are you observing for the event (becoming employed) only for the AIDS  
patient or for any household member?
	do you have multiple observations (in which case a time-dependent  
model can be built)?

If the answer to that last question is yes, then a relevant paper may  
be:
Fewell, Z., M. A. Hernan, et al. (2004). "Controlling for time- 
dependent confounding using marginal structural models." The Stata  
Journal 4(4): 402-20

Michael McCulloch


On Aug 12, 2010, at 12:32 PM, Nyasha Tirivayi wrote:

> Hello
>
> I would like to model  intrahousehold transitions from unemployment to
> employment. In the household are:
> 1. A patient receiving AIDS medication
> 2. And non-patient household members living together with the patient.
>
> I am thinking of applying the cox proportional hazard model, where
> duration of AIDS medication is the time variable. How can  I analyse
> the transitions by other non-patient family members, when they do not
> receive AIDS medication? Do I assign the time variable to the patient
> and his/her non-patient family members?
>
> Kindly advise
>
> Regards
>
> Nyasha Tirivayi
> Maastricht University
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Best wishes,

Michael McCulloch, LAc MPH PhD
Pine Street Foundation
124 Pine Street
San Anselmo, CA 94960-2674
tel:	415-407-1357
fax: 	206-338-2391

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