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st: pk analysis suite: elementary questions about -pkequiv-, -pkcross-, and -pkshape-
From
Michael McCulloch <[email protected]>
To
Statalist Statalist <[email protected]>
Subject
st: pk analysis suite: elementary questions about -pkequiv-, -pkcross-, and -pkshape-
Date
Fri, 19 Feb 2010 17:00:30 -0800
Hello Statalist friends,
I'm studying the manual (v11) for the pk suite, and have 3 questions:
1. Regarding the "carry" variable created by -pkshape-, in the manual
example (p. 1325), is "carry" simply an indicator that shows whether
or not a measurement was made in the same period/treatment
combination, so that if
"carry"==0, then no carryover is possible, and if
"carry"==A, then a carryover effect is possible, but no evidence yet?
2. Can -pkcross- be used in to compare treatment response (e.g. pain
score) in an AB-BA crossover study design, that was not a test of a
biopharmaceutical drug concentration?
3. -pkequiv- performs bioequivalence tests using serum levels of
biopharmaceutical drug concentration. Can the command also be used
instead to measure *any* continuous outcome, measured following some
other non-pharmaceutical intervention?
Best wishes,
Michael McCulloch
Pine Street Foundation
124 Pine Street
San Anselmo, CA 94960-2674
tel: 415-407-1357
fax: 206-338-2391
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