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st: Metan - possible to amend the ado to use difference confidence intervals?
From |
"Paul O'Brien" <[email protected]> |
To |
statalist <[email protected]> |
Subject |
st: Metan - possible to amend the ado to use difference confidence intervals? |
Date |
Wed, 24 Sep 2008 22:33:39 +0100 |
Having completed the meta-analysis of randomised trials of
intrauterine devices, I not want to combine all the individual results
in a graph where I input individual pregnancy rates and the standard
errors rather than risk difference estimates and their standard errors.
This is _not_ what metan is intended for, but it does what I want well
- produces the graphs I am looking for.
however, the confidence intervals calculated by metan gives impossible
values at the lower end when applied to individual rates - negative
rates.
For the confidence intervals I am using: p ^ exp(+/- 1.96s/(p x
ln(p))) as recommended by Kalbfleisch, J.D. and Prentice R.L. (1980).
The Statistical Analysis of Failure Time Data. I actually use p x 100
^ exp(+/- 1.96s/(p x ln(p/100))) as I have the data in percentages.
Would it be possible to change the metan ado to produce these
confidence intervals? I also want to produce summary rates, and tests
for heterogeneity.
Unfortunately, I have no experience of programming in Stata. I have
looked at the metan.ado but cannot see where an amendment might go.
I have lots of graphs of this sort to make with lost of data, so to be
able to automate it using metan would make a big difference to me.
Thanks for any help.
Paul
-------------------------------
Dr Paul O'Brien
Raymede Clinic
Westside Contraceptive Services
Westminster Primary Care Trust
Exmoor St
London
W10 6DZ
UK
44 + (0)20 8962 4450
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