Don't know if this would help, but we do PASS calcs for new tumor
markers like this: Set power and alpha at something reasonable
(reasonable to review boards, usually 80% and 0.05)and create a graph
showing a range of sample sizes plotted against a range of effect sizes.
-----Original Message-----
From: [email protected]
[mailto:[email protected]] On Behalf Of
[email protected]
Sent: Wednesday, October 26, 2005 6:19 AM
To: [email protected]
Subject: st: Sample size calculation
We are planning to measure some cytokines in patients with MS comparing
between a group with treatment and control, but there have not been
literatures regarding these measurements, so we do not have an estimated
mean and standard deviation. Is there a way to estimate a sample size?
(our IRB really wants to see sample size estimate.) Thanks.
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