Dear all,
Thanks to Kit Baum a new command called -genass- is now available from SSC.
-genass- is a simple wrapper command for performing basic statistical
genetic analyses of case-control association studies.
Main features
------------------
* Calculation of genotype and allele frequencies in cases and controls.
* Testing for Hardy-Weinberg equilibrium in cases and controls.
* Genotypic and allelic tests of association.
* Tests of association under dominant and recessive disease models.
* Test of association for additive/multiplicative disease model.
* Calculation of pair-wise LD.
The main advantage of the command is that results are collated into a
Stata formatted data set which can then be loaded into memory and the
results viewed (either graphically using -graph- commands, or by using
the -list- command).
Additional Features
-------------------
In addition to creating a Stata formatted data set, -genass- will (if
specified by the user), generate a series of graphs representing the
results, and/or generate a series of html formatted tables using Roger
Newson's -listtex- command.
Dependencies
--------------
As well as requiring Roger Newson's -listtex- command, this wrapper
also relies on the command -pwld- written by David Clayton. This is
part of his -genassoc- package which can be downloaded and installed
from his site using the following series of commands...
. net from http://www-gene.cimr.cam.ac.uk/clayton/software/stata
. net install genassoc
-genass- is currently written for Stata 8.0
Installation
--------------
For a description of -genass- type...
. ssc describe genass
...and to install, type...
. ssc install genass
...followed by...
. help genass
This is my first attempt at writing a Stata program (one that I am
willing to release to a wider audience anyway), and I already have one
thing "To Do", however, all comments and feedback, along with
additions to this "To Do" list are more than welcome.
Regards
Neil
To Do
--------
1. Make error messages more informative, so that reports are made as
to which marker is causing problem, and what that problem is.
*
* For searches and help try:
* http://www.stata.com/support/faqs/res/findit.html
* http://www.stata.com/support/statalist/faq
* http://www.ats.ucla.edu/stat/stata/
