Gary King has worked on similar problems.
http://gking.harvard.edu/stats.shtml
Some of the procedures are implemented in Stata.
Nick
[email protected]
[email protected]
>
> I've got to write a statistical analysis plan for measuring
> the differences
> between certain drugs on various event measures. For the binary events
> logistic regressions seem appropriate - whether the event
> occurs is the
> response and the predictors would include confounding factors
> measured at
> baseline (such as various severity measures).
> as well as dummy variables representing the drugs.
> I'm worried about two things related to the above:
> (1) It is quite possible that the events are rare.
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